hivfrenchresistance.org HIV French Resistance - HIV-1 genotypic drug resistance interpretation’s algorithms

hivfrenchresistance.org
Title: HIV French Resistance - HIV-1 genotypic drug resistance interpretation’s algorithms
Keywords: HIV, genotype, resistance, AC11, mutations, algorithm, antiretroviral, NRTI, NNRTI, PI
Description: HIV-1 genotypic drug resistance interpretation’s algorithms
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hivfrenchresistance.org Information

Website / Domain: hivfrenchresistance.org
Website IP Address: 158.255.101.87
Domain DNS Server: dns2.siteparc.fr,dns.siteparc.fr

hivfrenchresistance.org Rank

Alexa Rank: 19384111
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hivfrenchresistance.org Traffic & Earnings

Purchase/Sale Value: $5,736
Daily Revenue: $15
Monthly Revenue $471
Yearly Revenue: $5,736
Daily Unique Visitors 1,446
Monthly Unique Visitors: 43,380
Yearly Unique Visitors: 527,790

hivfrenchresistance.org WebSite Httpheader

StatusCode 200
Content-Type text/html
Date Tue, 02 Aug 2016 23:54:43 GMT
Server Apache

hivfrenchresistance.org Keywords accounting

Keyword Count Percentage
HIV 17 2.31%
genotype 0 0.00%
resistance 15 7.10%
AC11 2 0.35%
mutations 3 1.21%
algorithm 3 1.21%
antiretroviral 5 3.19%
NRTI 0 0.00%
NNRTI 0 0.00%
PI 11 0.98%

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HIV French Resistance - HIV-1 genotypic drug resistance interpretation’s algorithms Home Board Tables of Rules HIV tropism Archives HIV-1 RT and protease sequencing and drug susceptibility testing have been done in research settings for more than ten years to elucidate the genetic mechanisms of resistance to antiretroviral drugs. The accumulation of retrospective and prospective data has led expert panels to recommend the use of resistance testing in the decision of treatment of HIV-infected patients. The French ANRS (National Agency for AIDS Research) AC11 Resistance group provides HIV-1 genotypic drug resistance interpretation’s algorithms in order to guide physicians in the choice of antiretroviral treatment.These algorithms are mainly based on correlation between drug resistance mutations and virological outcome from patients failing antiretroviral therapy. The rules are presented as tables listing mutations conferring genotypic resistance or possible genotypic resistance to anti-HIV drugs and will be updated regularly. . January 2015 HIV-1 PCR and Sequencing Procedures . September 2015 Last tables of rules HIV-1(V25) Last tables of rules HIV-2(V25) NGS procedure HIV-1 subtyping Greg+, a molecular biology tool for mutation detection, analysis and interpretation RECOMMANDATIONS OF THE ANRS AC11 RESISTANCE GROUP HIV drug-resistance testing in plasma is recommended in persons with HIV infection at entry into care regardless of whether antiretroviral therapy (ART) will be initiated immediately or deferred. Genotypic testing in plasma is recommended as the preferred resistance testing to guide therapy in antiretroviral (ARV)-naive patients. Standard genotypic drug-resistance testing in plasma in ARV-naive persons involves testing for mutations in the reverse transcriptase (RT), protease (PR) and integrase (IN) genes. HIV drug-resistance testing in plasma should be performed to assist in the selection of active drugs when changing ARV regimens in persons with virologic failure (confirmed plasma HIV RNA >50 copies/mL). In persons with plasma HIV RNA >50 but 50 copies/mL in CSF of a patient treated by ARV, genotypic resistance testing should be performed on the CSF. ARV drug level measurements should be also performed in CSF.

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